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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESCO2
All Species:
3.64
Human Site:
S368
Identified Species:
10
UniProt:
Q56NI9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56NI9
NP_001017420.1
601
68307
S368
N
T
N
T
R
D
T
S
K
K
T
K
D
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543224
598
67974
D370
D
T
N
K
E
T
E
D
Q
L
I
I
D
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIB9
592
67255
G377
D
Q
L
V
I
D
A
G
Q
K
H
F
G
T
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508920
682
76075
R421
D
L
S
S
L
G
S
R
T
S
I
D
V
A
S
Chicken
Gallus gallus
XP_420012
679
73766
L441
K
S
K
R
A
R
E
L
S
K
Q
S
N
D
Q
Frog
Xenopus laevis
NP_001089603
640
69941
K400
R
F
P
K
Q
G
K
K
K
R
E
G
K
K
V
Zebra Danio
Brachydanio rerio
Q5SPR8
609
68341
K373
S
M
L
R
R
E
M
K
K
Q
T
D
N
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791750
838
93461
S490
M
S
S
T
P
N
S
S
K
K
S
Q
P
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146746
323
35496
R138
C
M
S
K
S
K
V
R
E
V
I
T
V
V
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
74.2
N.A.
69
N.A.
N.A.
45.8
37.4
36.7
37.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
84.1
N.A.
80
N.A.
N.A.
60.4
53.4
51.5
53.5
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
0
6.6
6.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
26.6
N.A.
N.A.
26.6
20
33.3
60
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
21.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
0
0
0
0
0
0
23
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
0
23
0
12
0
0
0
23
23
12
0
% D
% Glu:
0
0
0
0
12
12
23
0
12
0
12
0
0
0
12
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
23
0
12
0
0
0
12
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
34
12
0
0
0
% I
% Lys:
12
0
12
34
0
12
12
23
45
45
0
12
12
12
0
% K
% Leu:
0
12
23
0
12
0
0
12
0
12
0
0
0
0
34
% L
% Met:
12
23
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
23
0
0
12
0
0
0
0
0
0
23
0
0
% N
% Pro:
0
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
12
0
0
12
0
0
0
23
12
12
12
0
23
12
% Q
% Arg:
12
0
0
23
23
12
0
23
0
12
0
0
0
12
0
% R
% Ser:
12
23
34
12
12
0
23
23
12
12
12
12
0
0
12
% S
% Thr:
0
23
0
23
0
12
12
0
12
0
23
12
0
12
12
% T
% Val:
0
0
0
12
0
0
12
0
0
12
0
0
23
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _